发明名称 |
G-PROTEIN COUPLED RECEPTORS AND USES THEREFOR |
摘要 |
The invention provides isolated nucleic acids molecules, designated flh84g5 nucleic acid molecules, which encode polypeptides having high sequence homology to G-protein coupled receptors. The invention also provides antisense nucleic acid molecules, expression vectors containing flh84g5 nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which an flh84g5 gene has been introduced or disrupted. The invention still further provides isolated flh84g5 polypeptides, fusion polypeptides, antigenic peptides, and anti-flh84g5 antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
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申请公布号 |
CA2312478(A1) |
申请公布日期 |
1999.06.10 |
申请号 |
CA19982312478 |
申请日期 |
1998.12.04 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
GLUCKSMANN, M. ALEXANDRA;XIE, MICHAEL;GOODEARL, ANDREW D. J.;DISTEFANO, PETER |
分类号 |
C12N15/09;A61K38/00;C07K14/705;C07K16/28;C12N5/10;C12N15/12;C12P21/02;C12Q1/68;C12R1/91;(IPC1-7):C12N15/12;C12N15/63;C12N15/70;C12N15/74;C12N15/79;C12N15/81 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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