摘要 |
Quinazoline derivatives represented by formula (I) or salts thereof: wherein R<1> and R<2> each represents hydrogen, lower alkyl, lower alkoxyalkyl, etc.; R<3> represents hydrogen, lower alkyl, optionally substituted amino, etc.; R<4> represents hydrogen, lower alkyl, etc.; R<5> and R<6> each represents hydrogen or lower alkyl; X represents a single bond, lower alkylene, etc.; C<u>...</u>Y represents CH-OH, C=O, etc.; a is 0 or 1; and A represents aryl, heterocycle, aralkyl, etc. The compounds have an affinity for a serotonin 4 receptor and are useful as a remedy for digestive diseases, etc. |