发明名称 Intermediate Compound for Docetaxel Synthesis and Method for Its Production
摘要 <p>1. Technical Result Increase in docetaxel yield. 2. Essence A compound of the formula as an intermediate compound for docetaxel synthesis. A method comprises acylating 10-deacetyl baccatin III with at least 1,5 equivalent of n-bytil lithium and at least 1,5 equivalent of benzyl chloroformiate in tetrahydrofuran. The reaction is conducted at a low temperature - 200 C. 3. Field of Application Organic chemisry.</p>
申请公布号 GEP20002270(B) 申请公布日期 2000.07.10
申请号 GE1997AP03355 申请日期 1997.02.27
申请人 NAPRO BIOTHERAPEUTICS, INC.;BRYN MAWR COLLEGE 发明人 SISTI, NICHOLAS, J.;SWINDELL, CHARLES, S.;MADHAVI, C. CHANDER
分类号 C07D305/14 主分类号 C07D305/14
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