发明名称 |
Methods to detect protein trafficking disorders |
摘要 |
The present invention relates to methods of treating and diagnosing protein trafficking disorders and controlling secretory protein production. The present invention also relates to methods for folding unfolded proteins, especially in heterelogous expression systems. The methods comprise exposing an unfolded protein to a biological preparation comprising ERp57 in combination with calnexin or calreticulin under conditions to permit folding of the unfolded protein. |
申请公布号 |
AU5667700(A) |
申请公布日期 |
2001.01.22 |
申请号 |
AU20000056677 |
申请日期 |
2000.06.27 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
DANIEL C. TESSIER;ANDRE ZAPUN;JOHN J. M BERGERON;DAVID Y THOMAS |
分类号 |
A61K38/17;C12Q1/26;G01N33/573;G01N33/68 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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