9{60 -UNSUBSTITUTED-11{62 -BROMO-19-NORSTEROIDS

摘要

9 alpha -UNSUBSTITUTED-11 beta -BROMO-19-NOR-STEROIDS HAVING HORMONAL ACTIVITY AND A PROCESS FOR PREPARING SAME BY REACTING THE CORRESPONDING 11 alpha -HYDROXY STEROID WITH A. A REAGENT OF THE FORMULA WHERE R1 and R2 are alkyl groups having 1-8 carbon atoms or aralkyl or aryl groups or, together with the nitrogen atom to which they are attached, comprise a heterocyclic radical; R3 is a bromine or fluorine atom; R4 is a bromine or fluorine atom and R5 is hydrogen or R4 and R5 together represent a carbon-carbon bond; R6 is a chlorine, bromine or fluorine atom and R7 is a chlorine, bromine or fluorine atom or a trifluoromethyl group, the reaction being effected in the presence of bromide ions when neither R3 nor R4 is bromine; or (b) with a triaryl-phosphine or -phosphite and bromine or bromalkane.