发明名称 SALTS OF PHENYL-ALKANOIC ACIDS
摘要 The present invention provides a method of relieving pain and of treating inflammatory conditions in warm-blooded animals, including humans, which comprises administering to a warm-blooded animal suffering from an inflammatory condition a phenyl-alkanoic acid salt of the general formula: <IMAGE> wherein R1 is a hydrogen atom or a methyl radical, R2 is a halogen atom or an alkyl radical containing up to 5 carbon atoms, which may be straight-chained or branched, for example an isobutyl radical, or is a cyclohexyl radical or is a phenoxy or benzoyl radical, which may be substituted by one or two halogen atoms, R3 is a hydrogen atom or an allyloxy radical or R2 and R3, together with the phenyl nucleus to which they are attached, represent a naphthyl ring system containing a methoxy substituent, B is a primary, secondary or tertiary amino group or a guanidino or amidino group and n is a whole number not greater than 5, for example B is an amino group and n is 3 (ornithine), B is an amino group and n is 4 (lysine) or B is a guanidino radical and n is 3 (arginine).
申请公布号 AU7880375(A) 申请公布日期 1976.09.09
申请号 AU19750078803 申请日期 1975.03.05
申请人 SPA SOCIETA PRODOTTI ANTIBIOTICI, S.P.A. 发明人 TIBERIO BRUZZESE;RODOLFO FERRARI
分类号 A61K31/205;A61P29/00;C07C51/00;C07C51/41;C07C57/30;C07C57/46;C07C57/52;C07C57/58;C07C59/64;C07C59/68;C07C59/76;C07C59/84;C07C67/00;C07C227/18;C07C229/26;C07C239/00;C07C279/14 主分类号 A61K31/205
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