MEDICAL COMPOSITION FOR EXTERNAL APPLICATION

摘要

A medical composition for external application comprises a dialkyl phosphate represented by the formula: wherein R1 and R2 independently represent a hydrocarbon group having from 6 to 24 carbon atoms, R3 and R4 independently represent hydrocarbon group having from 2 to 6 carbon atoms, m and n independently represent a value of from 0 to 20, and x represents a hydrogen atom or a salt of an alkali metal and the like. In the presence of the dialkyl phosphate, percutaneous intake of medically active ingredients is highly enhanced. Examples of the medically active ingredients directed to in the invention include antiinflammatory agents such as ethyl aminobenzoate; adrenocortical hormones such as hydrocortisone; etc. The inventive composition is highly safe without giving any stimulation to the skin.