发明名称 PROCESS AND REAGENT FOR THE SPECIFIC DETERMINATION OF PANCREATIC -AMYLASE
摘要 Process and reagent for the specific determination of pancreatic .alpha.-amylase The present invention provides a process for the specific determination of pancreatic .alpha.-amylase in the presence of salivary .alpha.-amylase in body fluids, especially in serum plasma, duodenal juices or urine, by reaction with a system for the detection of .alpha.-amylase in the presence of a monoclonal antibody which reacts with salivary .alpha.-amylase, wherein a monoclonal antibody is used which specially inhibits the salivary enzyme but does not inhibit the pancreatic enzyme by more than 50%. The present invention also provides a reagent for the specific determination of pancreatic .alpha.-amylase in the presence of salivary .alpha.-amylase in body fluids, especially in serum, plasma, duodenal juices or urine, comprising a system for the detection of .alpha.-amylase and a monoclonal antibody against salivary .alpha.-amylase, wherein it contains a monoclonal antibody which specifically inhibits the salivary enzyme but does not inhibit the pancreatic enzyme by more than 50%.
申请公布号 CA1277231(C) 申请公布日期 1990.12.04
申请号 CA19860499237 申请日期 1986.01.08
申请人 NAUJOKS, KURT 发明人 NAUJOKS, KURT;WULFF, KARL;GERBER, MARTIN
分类号 G01N33/50;A61K39/00;C12P21/08;C12Q1/40;C12R1/91;G01N33/573 主分类号 G01N33/50
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