发明名称 |
METHOD FOR PRODUCING HETEROCYCLIC KETONE DERIVATIVES AND MEDICAL PREPARATIVES CONTAINING THEM |
摘要 |
<p>A compound of the formula: <CHEM> wherein R<1> is H or an optionally substituted hydrocarbon or acyl group; ring A is an optionally further substituted benzene ring; n is an integer of 1 to 10; R<2>, R<3> and R<4> are H or an optionally substituted hydrocarbon group; R<3> and R<4> may form an optionally substituted heterocyclic group, taken together with the adjacent nitrogen atom; k is an integer of 0 to 3; and m is an integer of 1 to 8; provided that when k=0 and m=2, n is an integer of not less than 2 or a pharmaceutically acceptable salt thereof, exhibiting excellent cholinesterase inhibitory activity and monoamine reuptake inhibitory activity, thus being useful as therapeutic/prophylactic medicaments of senile dementia.</p> |
申请公布号 |
HU9300659(D0) |
申请公布日期 |
1993.05.28 |
申请号 |
HU19930000659 |
申请日期 |
1993.03.09 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES LTD.,JP |
发明人 |
GOTO,GIICHI,JP;MIYAMOTO,MASAOMI,JP;ISHIHARA,YUJI,JP |
分类号 |
C07D209/08;C07D215/08;C07D223/16;C07D225/06;C07D401/04;C07D401/06;C07D401/12;C07D405/12;C07D417/12;C07D471/10 |
主分类号 |
C07D209/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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