发明名称 Process for production of diacetylrhein
摘要 The present invention provides a process for obtaining diacetylrhein, wherein diacetylrhein containing aloe-emodin components is subjected to a liquid-liquid partitioning between a polar organic solvent which is only partly miscible with water and an aqueous phase of pH 6.5. to 7.5 and the diacetylrhein is recovered and optionally recrystallised. The present invention is also concerned with diacetylrhein obtainable by this process and with pharmaceutical compositions containing it.
申请公布号 US5391775(A) 申请公布日期 1995.02.21
申请号 US19940236682 申请日期 1994.04.29
申请人 MADAUS AG 发明人 CARCASONA, ALFONS;GRIMMINGER, WOLF;HEITALA, PENTTI;WITTHOHN, KLAUS;ZAESKE, HELGA
分类号 A61K31/22;A01N37/10;A61K31/19;A61K31/192;A61K31/222;A61K31/235;A61K36/18;A61P19/02;A61P25/04;A61P29/00;C07C67/48;C07C67/52;C07C67/58;C07C69/00;C07C69/157;C07C69/16;C07C69/95;(IPC1-7):C07C50/34 主分类号 A61K31/22
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