发明名称 Pyrimidine derivatives as modulators of chemokine receptor activity
摘要 Compounds of formula (1), pharmaceutically acceptable salts, solvates and in vivo hydrolysable esters thereof, have activity as pharmaceuticals, in particular as modulators of chemokine receptor (especially CXCR2) activity, and may be in the treatment (therapeutic or prophylactic) of conditions/diseases in human and non-human animals which are exacerbated or caused by excessive or unregulated production of chemokines.
申请公布号 US7482355(B2) 申请公布日期 2009.01.27
申请号 US20050525495 申请日期 2005.02.23
申请人 ASTRAZENECA AB 发明人 EBDEN MARK RICHARD;MEGHANI PREMJI;COOK ANTHONY RONALD;STEELE JOHN;CHEEMA LAL LASHKAR SINGH
分类号 C07D239/56;A61K31/513;A61P9/10;A61P19/02;A61P19/10;A61P37/06;A61P37/08;C07D239/60;C07D401/04;C07D401/12;C07D403/12;C07D413/04;C07D413/12;C07D413/14;C07D417/12 主分类号 C07D239/56
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