发明名称 Bicyclic pyrazolone cytokine inhibitors
摘要 The present invention relates to 6,7-dihydro-5H-pyrazolo[1,2alpha]pyrazol-1-ones which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 6,7-dihydro-5H-pyrazolo[1,2alpha]pyrazol-1-ones and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.
申请公布号 US7482356(B2) 申请公布日期 2009.01.27
申请号 US20040983114 申请日期 2004.11.05
申请人 THE PROCTER & GAMBLE COMPANY 发明人 CLARK MICHAEL PHILIP;LAUGHLIN STEVEN KARL;GOLEBIOWSKI ADAM;BRUGEL TODD ANDREW;SABAT MARK
分类号 C07D487/04;A61K31/4162;A61K31/506 主分类号 C07D487/04
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