发明名称 |
METHODS FOR REDUCING CD36 EXPRESSION |
摘要 |
Provided in the present invention is a method for reducing CD36 expression within a cell. The method comprises a step of making a cell contact with the effective amount of aromatic-cationic peptide having one or more net positive charges; at least four amino acids; and at most about 20 amino acids, and satisfying relation, between minimum number (pm) of net positive charges and total number (r) of amino acid residues, that 3 pm is a maximum value among values of r+1 or less; and relation between a minimum value (a) of an aromatic group and total number (pt) of net positive charges, that 2a is a maximum value among values of pt+1 or less (except for the case that a is 1, and pt is 1). |
申请公布号 |
KR20160057372(A) |
申请公布日期 |
2016.05.23 |
申请号 |
KR20160057030 |
申请日期 |
2016.05.10 |
申请人 |
CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
SZETO HAZEL H.;LIU SHAOYI;CHO SUNGHEE |
分类号 |
A61K38/07;A61K38/03;A61K38/08;A61K38/10;A61K48/00;C07K5/103;C07K5/107;C07K5/11;C07K5/117;C07K14/705 |
主分类号 |
A61K38/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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