Biomolecule detection apparatus including plurality of electrodes

摘要

A biomolecule detection apparatus comprising a nanopore device having a front surface and rear surface and including a nanopore having a nano-sized diameter; a reservoir disposed adjacent to a rear surface of the nanopore device; and a power supply unit comprising a first electrode disposed in a front of the nanopore device; a second electrode disposed inside the reservoir; and a third electrode disposed adjacent the nanopore and between the first electrode and the second electrode; as well as a method of using the biomolecule detection apparatus to detect a biomolecule in a sample.

主权项

1. A biomolecule detection apparatus comprising:
a nanopore device having a front surface and a rear surface and including a nanopore having a nano-sized diameter; a reservoir disposed adjacent to the rear surface of the nanopore device; and a power supply unit comprising
a first electrode positioned in front of the nanopore device;a second electrode disposed inside the reservoir, wherein the nanopore device is positioned between the first and second electrodes; anda third electrode disposed between the first electrode and the second electrode on the front surface of the nanopore device adjacent to the nanopore, wherein the nanopore connects the front and the rear surfaces of the nanopore device, and is connected to the reservoir, and wherein the power supply unit is configured to provide voltage signals to the first electrode, the second electrode and the third electrode to produce an electric field that induces target biomolecules contained in a sample proximal the front surface of the nanopore device to pass through the nanopore into the reservoir.