Solid dosage form comprising micronized cytisine and its production method

摘要

The subject of the present invention is solid dosage form containing cytisine and ancillary substances characterised in that it contains from 0.1% to 5% micronised cytisine, wherein all molecules have a diameter less than from 10 μπι, corn starch from 40% to 60%, preferably 99.9% particles sized from 5 μπι to 25 μπι, macrocrystalline cellulose in an amount from 40% to 60%, preferably the particle size is: 99% below 38 μπι, wherein the mass ratio of ancillary substances to the active ingredient is from 1:19 to 1:999 and is in the form of a hard capsule as well as a method of obtaining it.

主权项

1. A solid dosage form containing cytisine and ancillary substances, wherein the solid dosage form contains:
from 0.1% to 5% micronised cytisine, wherein all molecules have a diameter less than 10 μm, corn starch from 40% to 60%, and microcrystalline cellulose in an amount from 40% to 60%, and wherein the mass ratio of the active ingredient to ancillary substances is from 1:19 to 1:999 and is in the form of a hard capsule.