| 发明名称 | Methods for the treatment of HER2 amplified cancer | ||
| 摘要 | Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib. | ||
| 申请公布号 | US9415050(B2) | 申请公布日期 | 2016.08.16 |
| 申请号 | US201414458157 | 申请日期 | 2014.08.12 |
| 申请人 | Pharmacyclics LLC | 发明人 | Chen Jun;Buggy Joseph J.;Elias Laurence |
| 分类号 | A61K31/454;C07D487/04;A61K31/519;A61K45/06 | 主分类号 | A61K31/454 |
| 代理机构 | Foley Hoag LLP | 代理人 | Foley Hoag LLP |
| 主权项 | 1. A method for treating a refractory HER2-amplified breast cancer in an individual in need thereof comprising administering to an individual in need thereof a composition comprising (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one | ||
| 地址 | Sunnyvale CA US | ||