| 发明名称 | Methods for making active crystalline materials | ||
| 摘要 | The present invention relates to an active crystalline material, especially an active multicomponent crystalline material such as a salt or a cocrystal, which may be made by dispersing precursor components of the active crystalline material in a liquid medium which comprises an anti-solvent, maintaining the dispersion for a period during which the active crystalline material is formed, and, during said period, exposing the dispersion to a solvent, which solvent being present in the liquid medium in a minor proportion by weight thereof. | ||
| 申请公布号 | US9439914(B2) | 申请公布日期 | 2016.09.13 |
| 申请号 | US201314651404 | 申请日期 | 2013.12.11 |
| 申请人 | CPI Innovation Services Limited | 发明人 | Ahmad Ruksanna;Cooper Jeremy;Odiase Isaac |
| 分类号 | A01N43/90;A61K31/52;A61K31/60;A61K31/522;A61K31/194;A61K31/455;A61K31/55;A61K31/505;C07B63/00 | 主分类号 | A01N43/90 |
| 代理机构 | Pepper Hamilton LLP | 代理人 | Pepper Hamilton LLP |
| 主权项 | 1. A method for making an active crystalline material, the method comprising: dispersing precursor components of the active crystalline material in a liquid medium comprising an anti-solvent to generate a dispersion; maintaining the dispersion for a period sufficient to form the active crystalline material; and exposing the dispersion to a solvent, where the solvent is present in the liquid medium in a minor proportion by weight thereof. | ||
| 地址 | Redcar GB | ||