发明名称 |
METHOD FOR DETERMINING ANTIBIOTICS WITH beta -LACTAM CORE IN A BIOLOGICAL FLUID |
摘要 |
The invention concerns a method for detecting antibiotics with beta -lactam core in a biological fluid comprising the following steps: a) contacting a specific volume of said biological fluid with an amount of identifying agent and incubating the resulting mixture in conditions for forming a complex of the antibiotics possibly present in said biological fluid with the identifying agent; b) contacting the mixture resulting from step a) with at least a reference antibiotic immobilised on a support, in conditions for forming a complex of the reference antibiotic with the amount of identifying agent which has not reacted in step a); and c) determining the amount of identifying agent fixed on the support. The invention is characterised in that the identifying agent comprises a receptor sensitive to antibiotics with beta -lactam core obtained from Bacillus licheniformis. |
申请公布号 |
WO9967416(A3) |
申请公布日期 |
2000.04.27 |
申请号 |
WO1999EP02166 |
申请日期 |
1999.03.30 |
申请人 |
UCB-BIOPRODUCTS, S.A. |
发明人 |
DEGELAEN, JACQUES;GRANIER, BENOIT;FRERE, JEAN-MARIE;JORIS, BERNARD |
分类号 |
G01N33/50;C12Q1/00;C12Q1/06;G01N33/04;G01N33/15;G01N33/543;G01N33/558;G01N33/566 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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