发明名称 Amphetamine derivatives
摘要 Compounds having the general formula <IMAGE> I or pharmaceutically acceptable salts thereof, in which formula R1 and R2 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R3 represents a lower alkyl group or a benzyl group, R4 represents a hydrogen atom, a lower alkyl group, a benzyl group or a CH2CH2CH2-bridge connected to the phenyl ring in ortho-position relative to the N-substituent, R5 represents a hydrogen atom or a methyl group and R6 represents a lower alkyl group, provided that R1 and/or R2 represents a lower alkyl group or a halogen atom when R3 represents a methyl group, R4 represents a methyl group and R5 represents a hydrogen atom; methods for the preparation thereof; intermediates useful for their preparation; pharmaceutical preparations containing at least one of these compounds; and the use thereof in the treatment of depressive states and alleviating anxiety.
申请公布号 US3996381(A) 申请公布日期 1976.12.07
申请号 US19740497295 申请日期 1974.08.14
申请人 ASTRA LAKEMEDEL AKTIEBOLAG 发明人 FLORVALL, GOSTA LENNART;ROSS, SVANTE BERTIL;OGREN, SVEN-OVE
分类号 A61K31/135;A61K31/137;A61K31/47;A61P25/24;A61P25/26;C07C67/00;C07C209/00;C07C209/34;C07C209/62;C07C211/49;C07C211/52;C07C211/53;C07D215/06;C07D215/12;C07D215/14;C07D215/18;(IPC1-7):A61K31/13 主分类号 A61K31/135
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