发明名称 2-[2H-(1,3-dihydroisoindole)alkylene]-4,5-dihydroimidazoles and pharmaceutical compositions thereof
摘要 A compound of formula (I): <IMAGE> (I) or a pharmaceutically acceptable salt, ester or amide thereof, wherein: Z represents a residue of a substituted or unsubstituted aryl group, X represents O or NRo wherein Ro represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, an alkanoyl group substituted or unsubstituted in the alkyl moiety, or an arylalkyl moiety substituted or unsubstituted in the aryl moiety. n represents an integer 1 or 2, m represents an integer 1 or 2, p represents an integer 2 or 3, and q represents an integer in the range of from 1 to 12; pharmaceutical compositions containing such compounds and the use of such compounds and compositions in medicine.
申请公布号 US4863946(A) 申请公布日期 1989.09.05
申请号 US19860936162 申请日期 1986.12.01
申请人 BEECHAM GROUP PLC 发明人 BERGE, JOHN M.
分类号 A61K31/415;A61K31/47;A61K31/472;A61P3/06;A61P3/08;C07D209/44;C07D217/04;C07D401/06;C07D403/06 主分类号 A61K31/415
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