发明名称 |
Amino-substituted bisphosphonic acids |
摘要 |
1-Aminoalkyliden-1,1-bisphosphonic acids of formula (B), or any salt thereof: <CHEM> wherein R2 is a straight-chain or branched aliphatic hydrocarbon radical of 1-9 carbon atoms, which is optionally substituted by one or more amino or aminoalkyl groups with the exception of a terminal aminoalkyl group <CHEM> wherein R3 is a straight-chain or branched, saturated or unsaturated aliphatic hydrocarbon radical of 1-9 carbon atoms, and R4 is cyclohexyl or cyclohexylmethyl, benzyl or a straight-chain or branched, saturated or unsaturated aliphatic hydrocarbon radical of 4-18 carbon atoms, as a single substituent of R2. |
申请公布号 |
EP0753523(A1) |
申请公布日期 |
1997.01.15 |
申请号 |
EP19950110706 |
申请日期 |
1995.07.10 |
申请人 |
GADOR S.A.;UNIVERSITY OF LEIDEN |
发明人 |
PAPAPOULOS, SOCRATES;VAN BEEK, E.R.;LOWICK, C.W.G.M.;LABRIOLA, RAFAEL;VECCHIOLI, ADRIANA |
分类号 |
A61K47/24;A61K31/66;A61K33/06;A61K33/16;C07F9/38 |
主分类号 |
A61K47/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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