发明名称 Amino-substituted bisphosphonic acids
摘要 1-Aminoalkyliden-1,1-bisphosphonic acids of formula (B), or any salt thereof: <CHEM> wherein R2 is a straight-chain or branched aliphatic hydrocarbon radical of 1-9 carbon atoms, which is optionally substituted by one or more amino or aminoalkyl groups with the exception of a terminal aminoalkyl group <CHEM> wherein R3 is a straight-chain or branched, saturated or unsaturated aliphatic hydrocarbon radical of 1-9 carbon atoms, and R4 is cyclohexyl or cyclohexylmethyl, benzyl or a straight-chain or branched, saturated or unsaturated aliphatic hydrocarbon radical of 4-18 carbon atoms, as a single substituent of R2.
申请公布号 EP0753523(A1) 申请公布日期 1997.01.15
申请号 EP19950110706 申请日期 1995.07.10
申请人 GADOR S.A.;UNIVERSITY OF LEIDEN 发明人 PAPAPOULOS, SOCRATES;VAN BEEK, E.R.;LOWICK, C.W.G.M.;LABRIOLA, RAFAEL;VECCHIOLI, ADRIANA
分类号 A61K47/24;A61K31/66;A61K33/06;A61K33/16;C07F9/38 主分类号 A61K47/24
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