SUBSTITUTED 6-R-1,3,4-THIADIAZINE-2-AMINES, THE USE THEREOF AS ANAESTHETISING, CARDIOVASCULAR AND HYPOMETABOLIC AGENTS, AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM

摘要

The disclosure relates to substituted 6-R-1,3,4-thiadiazine-2-amines of general formula (I), in which Ar stands for phenyl which may be substituted with one or more atoms of chlorine, bromine, C1-C4 alkoxy or C1-C4 alkyl groups; R<1> and R<2> each independently of one another represent a hydrogen atom or a C1-C4 alkyl residue; and R<3> and R<4> are independently selected from C1-C4 alkyl groups. Also disclosed are the pharmacologically acceptable salts of these compounds, their use as anaesthetising, cardiovascular and hypometabolic agents and a pharmaceutical composition containing them.