| 摘要 |
<p>A carotene conjugate of formula (I), where R1 is hydrogen or methyl; R2 is formula (a); R?3, R4 and R5¿ are independently, hydrogen, methyl or ethyl; R?6 and R7¿ are independently -R?13, -OR13, -C(R16¿)(O), -C(R16)2OR13, -CH=CHR13, or -(CH¿2?)R?14; R8 is -R13, -OR13, -C(R16¿)(O), -C(R16)2OR13, -CH=CHR13, or -(CH¿2)R?14 or taken with R10 is =O; R?9 is -R13, -OR13, -C(R16¿)(O), -C(R16)2OR13, -CH=CHR13, or -(CH¿2)R?14 or taken with R10 is a chemical bond; R?10 is -R13, -OR13, -C(R16¿)(O), -C(R16)2OR13, -CH=CHR13, or -(CH¿2)R?14 or taken together with R9 is a chemical bond or taken with R8 is =O; R?11 is R13¿, or -OR13; R12 is -C(R13)2C(Y)-, -C(O)O(O)C-, -C(NR13)O(O)C-, or -C(O)N(R15)-C(O)-; R13 is, independently at each occurrence, hydrogen or lower alkyl of from 1 through about 10 carbon atoms; R14 is an amino acid residue, R?15 is -R13, -R14¿, or -C(O)NHR13; R16 is, independently at each occurrence, hydrogen or lower alkyl of 1 to about 4 carbon atoms and Y is =O, =S, or 2H-.</p> |
