Quantitative perfusion analysis

摘要

A system is disclosed for quantitative analysis of perfusion images comprising image elements having intensity values associated therewith. The system comprises a frequency distribution computing subsystem (1) for computing a plurality of frequency distributions of the intensity values of at least part of the images. The system comprises a perfusion information extractor (2) for extracting information relating to perfusion from the plurality of frequency distributions. The perfusion information extractor (2) comprises a shift detector (3) for detecting a shift of the intensity values of the frequency distribution. The perfusion information extractor (2) is arranged for extracting the information relating to perfusion, based on the detected shift. A user interface element (8) enables a user to indicate a boundary between the core region and the rim region by a single degree of freedom. A vesselness subsystem (9) associates a vesselness value with an image element.

主权项

1. A system for quantitative analysis of perfusion images comprising image elements having intensity values associated therewith, comprising
a frequency distribution computing subsystem including a processor configured to compute a plurality of frequency distributions of the intensity values of at least part of the perfusion images, wherein the perfusion images include a plurality of images of a same region of interest at different time points over a predetermined period of time and include voxels or pixels with intensity values corresponding to a concentration of contrast agent uptake in tissue of the region of interest over the predetermined period of time; and a perfusion information extractor including the processor further configured to compare the plurality of frequency distributions with a single reference frequency distribution to detect respective shifts of respective frequency distributions relative to the reference frequency and extract information relating to perfusion from the plurality of frequency distributions based on the shifts, wherein the information relating to perfusion includes quantitative perfusion information about the contrast agent uptake.