Apparatus And Method For Filtration Of A Suspension

摘要

The present invention provides devices suitable for filtration including diafiltration of a suspension containing a species such as particles, cells or macromolecules, apparatus comprising such devices and methods of using the devices and apparatus. The devices of the invention comprise a vessel having a filter that divides the vessel into a first chamber and a second chamber provided with various outlet ports. Gas is used to finally concentrate the suspension (118) in the filtration chamber by displacing the liquid up to 95% through the filter (14).

主权项

1. A device for filtration of a liquid containing a species in suspension comprising a vessel, the vessel comprising a filter that divides the vessel into a first chamber and a second chamber, the first chamber comprising a first region and a second region wherein the second region is above the first region, the vessel being provided with:
(i) a lower port opening to the first region of the first chamber, configured to permit exit of a liquid containing the species from the first chamber, (ii) an upper port opening to the second region of the first chamber, and (iii) an outlet port opening to the second chamber.