IMMUNODIAGNOSTIC TEST FOR SYPHILIS AND OTHER TREPONEMAL INFECTIONS

摘要

IMMUNODIAGNOSTIC TEST FOR SYPHILIS AND OTHER TREPONEMAL INFECTIONS A component for the rapid detection of antiTreponemal antibodies or Treponemal immunogenic proteins adapted for use as a selective foundation material in standard immunoassays is provided. The component comprises a quantity of fibronectin protein adhered to an insoluble support matrix. The fibronectin component provides a foundation material for the selective binding of Treponemal protein immunogens, either in the form of whole Treponemal organisms or solubilized protein fractions thereof. Incorporation of the fibronectin component and either anti-Treponemal antibody or Treponemal protein immungens into a standard immunoassay test-pack provides an immunological assay for the presence of respective complementary Treponemal protein immunogen or antiTreponemal antibody in a biological sample.