DRUG-CONTAINING TRANSDERMAL PATCHES, PLASTISOLS AND ADHESIVES

摘要

Drug delivery polymer systems include hydrophobic polymer and a drug that has an aromatic ring. The system comprises, on a carrier (10), a layer (12) comprising the pressure sensitive adhesive having solids in which a drug is substantially soluble, a non-adhesive polymeric resin distributed uniformly through the adhesive. Another delivery system comprises a non-adhesive layer (14) of polymeric resin in which a drug component is substantially soluble and an adjoining adhesive band (18) arranged to hold the non-adhesive layer against the skin. The drug comprises at least 10 % by weight of the drug-containing layer, preferably in excess of 20 %, 30 % or 40 % by weight in both of the delivery systems.