| 发明名称 |
RATIONALLY DESIGNED HEPARINASES DERIVED FROM HEPARINASE I AND II |
| 摘要 |
Modified heparinases having altered binding specificity and activity are provided. Isolated nucleic acids encoding the same as well as vectors and host cells are provided. Methods for using the modified heparinases are also provided.
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| 申请公布号 |
WO0012726(A3) |
申请公布日期 |
2000.06.29 |
| 申请号 |
WO1999US19841 |
申请日期 |
1999.08.27 |
| 申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
SHRIVER, ZACHARY;VENKATARAMAN, GANESH;SASISEKHARAN, RAM;LIU, DONGFANG |
| 分类号 |
C12N15/09;A61K38/00;A61K38/51;A61P17/06;A61P27/02;A61P35/00;A61P43/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/88;C12N9/99;C12N15/60;C12Q1/527;C12Q1/68;(IPC1-7):C12N15/60;C12N11/00 |
主分类号 |
C12N15/09 |
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