发明名称 |
Benzimidazoles useful as protein kinase inhibitors |
摘要 |
Disclosed are compounds of formula (I), wherein: R1 is H or alkyl, R2 is optionally substituted aryl or heteroaryl, R3 is optionally substituted alkyl or -(CH2)n-L-R6, R4 is the group -C(Xb)NR5R6, Xa and Xb are oxygen or sulfur, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of disorders mediated by protein kinases.
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申请公布号 |
NZ533310(A) |
申请公布日期 |
2004.12.24 |
申请号 |
NZ20020533310 |
申请日期 |
2002.11.05 |
申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC |
发明人 |
CYWIN, CHARLES;LEE, JINBO;ROTH, GREGORY PAUL;SARKO, CHRISTOPHER RONALD;SNOW, ROGER JOHN;WILSON, NOEL STEWART;PULLEN, STEVEN S |
分类号 |
A61K31/4184;A61K31/422;A61K31/4439;A61P1/04;A61P3/10;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P25/28;A61P29/00;A61P35/00;A61P37/00;A61P37/04;A61P37/08;A61P43/00;C07D235/30;C07D401/12;C07D405/12;C07D409/12;C07D409/14;C07D413/12;(IPC1-7):A61K31/443;A61K31/418;C07D407/12 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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地址 |
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