| 摘要 |
Disclosed are a compound represented by the formula (II), a prodrug there of, a pharmaceutically acceptable salt of the compound or the prodrug, a pha rmaceutical agent and a pharmacologically composition each comprising the co mpound, and others. (II) wherein R1, R2, R3 and R4 is independently selected from a hydrogen atom, a C1-C6 alkyl group which may be substituted, a C7-C1 4 aralkyl group which may be substituted and -C(=O)Rx; Rx represents a C1-C6 alkyl group which may be substituted, an aryl group which may be substitute d, a heteroaryl group which may be substituted, a C1-C6 alkoxy group which m ay be substituted, or -NReRf; Ar1 represents an aromatic carbon ring which m ay be substituted and which may be fused, or an aromatic heterocyclic ring; Q represents -(CH2)m-(L)p- or -(L)p-(CH2)m-; m represents an integer selecte d from 0 to 2; n represents an integer selected from 1 and 2; p represents a n integer selected from 0 and 1; L represents -O-, -S- or -NR5-; and A repre sents an aryl group which may be substituted or a heteroaryl group which may be substituted.
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