发明名称 |
Treatment of vascular complications of diabetes |
摘要 |
A peptide consisting of 7-17 amino acids and including the adjacent hexamer TX1EX2X3E, where X1, X2 and X3 can be any natural or non natural amino acid, wherein the peptide does not exhibit TNF-receptor-binding activity and is cyclic, for the treatment or prevention of vascular complications in diabetes patients. |
申请公布号 |
US9359419(B2) |
申请公布日期 |
2016.06.07 |
申请号 |
US201013805839 |
申请日期 |
2010.10.20 |
申请人 |
Apeptico Forschung UND Entwicklung GMBH |
发明人 |
Fischer Bernhard;Lucas Rudolf |
分类号 |
A61K38/12;C07K7/64;A61K38/08;C07K14/525 |
主分类号 |
A61K38/12 |
代理机构 |
Chalker Flores, LLP |
代理人 |
Singleton Chainey P.;Flores Edwin S.;Chalker Flores, LLP |
主权项 |
1. A method for the treatment of vascular complications, except retinopathy, in diabetes patients comprising the step of:
administering to a diabetes patient, said diabetes patient being at risk of developing vascular complications, except retinopathy, or having vascular complications, except retinopathy, an amount of a peptide consisting of 7-17 amino acids and including the hexamer TX1EX2X3E, wherein X1, X2 and X3 can be any natural or non natural amino acid, wherein the peptide does not exhibit TNF-receptor-binding activity and is cyclic, for treatment of vascular complications, except retinopathy, in said patient. |
地址 |
Vienna AT |