| 发明名称 | Small molecule inhibitors of HIV proteases | ||
| 摘要 | Described herein are compounds, compositions, and methods for treating HIV and related diseases. | ||
| 申请公布号 | US9359317(B2) | 申请公布日期 | 2016.06.07 |
| 申请号 | US201414157042 | 申请日期 | 2014.01.16 |
| 申请人 | Purdue Research Foundation | 发明人 | Ghosh Arun K. |
| 分类号 | A61K31/34;C07D307/16;A61K31/341;C07D493/04;C07D207/48;C07D493/08;C07D493/18 | 主分类号 | A61K31/34 |
| 代理机构 | Schwegman Lundberg & Woessner, P.A. | 代理人 | Schwegman Lundberg & Woessner, P.A. |
| 主权项 | 1. A pharmaceutical composition comprising compound of the formula: Wherein: R1 is optionally substituted alkyl or aryl;R2 is hydrogen or optionally substituted alkyl;R5 is hydrogen, optionally substituted alkyl, optionally substituted alkenyl, or nitrile;R7 is hydrogen;R8 is optionally substituted arylalkyl; andR11 is hydrogen, alkyl, arylalkyl, or a pro-drug moiety; and one or more carriers, diluents or excipients, and combinations thereof. | ||
| 地址 | West Lafayette IN US | ||