| 摘要 |
1323453 Analgesic medicines CHOAY SA 7 Aug 1970 [8 Aug 1969] 38147/70 Heading A5B [Also in Division C2] Pharmaceutical compositions having analgesic activity, for oral, parenteral or rectal administration, comprise a compound of formula I: in which R 1 represents one or more substituents each attached at any available position on the phenyl nucleus and selected from -NO 2 , -OH, carbomethoxy, methyl-sulfonyl, halogen and alkyl groups containing one to three carbon atoms, two chlorine or methyl radicals not simultaneously occupying the 2 and 6 positions on the phenyl nucleus, or, except when R 2 is hydrogen and R 3 and R 4 are both ethyl groups, R 1 represents a hydrogen atom; R 2 is hydrogen or a methyl group; R 3 and R 4 are alkyl radicals containing from two to four carbon atoms, or together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heterocyclic group; and Y is an aliphatic divalent hydrocarbon group containing from two to four carbon atoms, or physiologically acceptable acid addition or quaternary ammonium salt thereof, together with a suitable pharmaceutical carrier, and, optionally, other active ingredients, e.g. quinine. |
