| 摘要 |
PURPOSE:To provide the titled preparation containing an encapsulated composition obtained by compounding an active component with an emulsion base consisting of a hydrophilic substance, an oily substance and a substance which is solid at room temperature, and able to control the dissolution time in body fluid by varying the relative ratios of the three components of the above emulsion base. CONSTITUTION:A mixture of (A) an active component and (B) an emulsion base consisting of a hydrophilic substance (e.g. macrogol, sugar, polyhydric alcohol, etc.), an oily substance (e.g. animal or vegetable food oil) and a substance which is solid at room temperature (e.g. beeswax, unsaponified soybean oil, etc.) is used as a content and encapsulated with gelatin to obtain the objective gelatin encapsulated preparation. The dissolution time of the capsule in body fluid can be freely controlled by varying the compositional ratios of the components of the emulsion base. The dissolution time is shortened by increasing the ratio of the hydrophilic substance in the emulsion base and is prolonged by increasing the ratio of the oily substance.
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