| 发明名称 |
POLYPROLYL INHIBITORS OF CYCLOPHILIN |
| 摘要 |
This invention relates to neurotrophic low molecular weight, small molecule peptidic cyclophilin inhibitor compounds having an affinity for cyclophilintype immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
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| 申请公布号 |
CA2263828(A1) |
申请公布日期 |
1998.06.18 |
| 申请号 |
CA19972263828 |
申请日期 |
1997.12.08 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
WEI, LING;HAMILTON, GREGORY S.;STEINER, JOSEPH P. |
| 分类号 |
A61K45/00;A61K38/07;A61K38/08;A61K38/55;A61P25/00;A61P25/16;A61P25/28;C07K5/10;C07K7/06;(IPC1-7):A61K38/03 |
主分类号 |
A61K45/00 |
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