| 发明名称 |
TREATMENT OF AUTOIMMUNE DISEASE USING TOLERIZATION IN COMBINATION WITH METHOTREXATE |
| 摘要 |
<p>A combination of a mucosally administrable bystander antigen and an orally, enterally, or parenterally administrable methotrexate is employed to make a pharmaceutical formulation and to treat or prevent autoimmune disease. The amounts of bystander antigen and methotrexate are effective in combination to suppress autoimmune response associated with the autoimmune disease.</p> |
| 申请公布号 |
WO9832451(A1) |
申请公布日期 |
1998.07.30 |
| 申请号 |
WO1998US01648 |
申请日期 |
1998.01.26 |
| 申请人 |
AUTOIMMUNE, INC. |
发明人 |
WEINER, HOWARD, L.;AL-SABBAGH, AHMAD;NELSON, PATRICIA, A. |
| 分类号 |
C07D475/08;A61K31/519;A61K38/00;A61K38/17;A61K38/26;A61K38/28;A61K38/39;A61K38/51;A61K39/00;A61P3/10;A61P19/04;A61P27/02;A61P29/00;A61P37/06;B41J2/21;H04N1/60;(IPC1-7):A61K35/30;A61K31/495;A61K31/50 |
主分类号 |
C07D475/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
