发明名称 |
INFLAMMATORY MEDIATION OBTAINED FROM ATRACTYLODES LANCEA |
摘要 |
The present invention provides a method for inhibiting the activity of cyclooxygenase-2 and other proinflammatory factors in a mammal. The method comprises administering to the mammal a therapeutically effective or prophylactically effective amount of an organic extract of Atractylodes lancea. The inhibitory effect of the organic extract of this invention on cyclooxygenase-2 activity is substantially greater than the inhibitory effect of the organic extract on cyclooxygenase-1 activity. The present invention also provided a method for treating a mammal having, or at risk for developing, a condition which is benefited by the inhibition of cyclooxygenase-2 or other proinflammatory factors. The method comprises administering to the mammal a therapeutically effective or prophylactically effective amount of the organic extract of Atractylodes lancea. |
申请公布号 |
WO0056348(A1) |
申请公布日期 |
2000.09.28 |
申请号 |
WO2000US07085 |
申请日期 |
2000.03.20 |
申请人 |
MONSANTO COMPANY;CORLEY, DAVID, G.;OBUKOWICZ, MARK |
发明人 |
CORLEY, DAVID, G.;OBUKOWICZ, MARK |
分类号 |
C12N9/99;A23L1/30;A61K;A61K36/16;A61K36/28;A61K36/284;A61K36/68;A61K36/81;A61K36/8962;A61P;A61P19/02;A61P25/00;A61P29/00;A61P29/02;A61P35/00;A61P43/00 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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