发明名称 |
Process for alkylating hindered sulfonamides. |
摘要 |
The present invention relates to a process for the preparation of compounds of formula (b), in which a compound of formula V is reacted with a compound of formula VI. The resulting compound of formula IV is reduced to a compound of formula III which is hydrolysed to a compound of formula (b). Alternatively, a compound of formula IV is hydrolysed to a compound of formula (a) which reduced to a compound of formula (b). Compounds of formula IV are novel. In the formulae the variables are as defined in the claims. <CHEM> |
申请公布号 |
ZA9902627(B) |
申请公布日期 |
2000.10.09 |
申请号 |
ZA19990002627 |
申请日期 |
1999.04.09 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
JOEL MICHAEL HAWKINS |
分类号 |
A61K31/223;A61K31/351;A61P1/00;A61P1/02;A61P1/04;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P17/02;A61P19/02;A61P19/10;A61P25/00;A61P25/04;A61P25/06;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P35/00;A61P35/04;A61P37/04;A61P37/06;A61P37/08;A61P43/00;B01J23/44;C07B61/00;C07C303/36;C07C303/40;C07C311/29;C07C311/37;C07D309/14;C07D311/00;C07D493/06;C07D493/08 |
主分类号 |
A61K31/223 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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