发明名称 |
ENZYMATIC ACTIVITY ASSAYS FOR I2S |
摘要 |
In certain embodiments of the present invention, kinetic parameters of I2S enzyme are determined. In some instances, a sample including I2S enzyme is incubated under defined conditions, with a series of determined amounts of I2S substrate including a detectable label. Following incubation, the reaction mixture can be analyzed, e.g., by a method including chromatography. A detection unit can be used to measure the presence of the detectable label. Data can be analyzed to determine kinetic parameters. |
申请公布号 |
WO2016100603(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
WO2015US66263 |
申请日期 |
2015.12.17 |
申请人 |
SHIRE HUMAN GENETIC THERAPIES, INC. |
发明人 |
BERNHARDT, PETER;TIEN, CLAIRE;FIELDING, ELISHA;CHHAJLANI, VIJAY |
分类号 |
C12Q1/34 |
主分类号 |
C12Q1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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