发明名称 VASCULAR ENDOTHELIAL GROWTH FACTOR-X
摘要 There is provided a novel vascular endothelial growth factor, herein designated VEGF-X, in addition to the nucleic acid molecule encoding it, a host cell transformed with said vector and compounds which inhibit or enhance angiogenesis. Also provided is the sequence of a CUB domain present in the sequence of VEGF-X which domain itself prevents angiogenesis and which is used to treat diseases associated with inappropriate vascularisation or angiogenesis.
申请公布号 WO0037641(A3) 申请公布日期 2000.10.19
申请号 WO1999US30503 申请日期 1999.12.21
申请人 JANSSEN PHARMACEUTICA N.V.;GORDON, ROBERT, DOUGLAS;SPRENGEL, JORG, JURGEN;YON, JEFFREY, ROLAND;DIJKMANS, JOSIENA, JOHANNA, HUBERDINA;GOSIEWSKA, ANNA;DHANARAJ, SRIDEVI, NAIDU;XU, JEAN 发明人 GORDON, ROBERT, DOUGLAS;SPRENGEL, JORG, JURGEN;YON, JEFFREY, ROLAND;DIJKMANS, JOSIENA, JOHANNA, HUBERDINA;GOSIEWSKA, ANNA;DHANARAJ, SRIDEVI, NAIDU;XU, JEAN
分类号 A61K38/00;A61P9/00;C07K14/52;C12N1/21;C12N15/12 主分类号 A61K38/00
代理机构 代理人
主权项
地址