发明名称 FOERFARANDE FOER FRAMSTAELLNING AV ANTIARYTMISKA VERKANDE BIS-HOMOFTALIMIDOALKYLAMINER
摘要 Compounds of the formula <IMAGE> wherein A and B, which may be identical to or different from each other, are each straight alkylene of 2 to 4 carbon atoms which may have a methyl or phenyl substituent attached thereto, R1, R2, R3 and R4, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, hydroxyl, amino, nitro, acetylamino, alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms or (alkyl of 1 to 3 carbon atoms)thio, R5, R6, R7 and R8, which may be identical to or different from each other, are each hydrogen, alkyl of 1 to 4 carbon atoms, phenyl-(alkyl of 1 to 4 carbon atoms) or methoxyphenyl-(alkyl of 1 to 4 carbon atoms), or R5 and R6, together with each other, are straight alkylene of 2 to 5 carbon atoms, or R7 and R8, together with each other, are straight alkylene of 2 to 5 carbon atoms, and R9 is hydrogen, alkyl of 1 to 6 carbon atoms or phenyl-(alkyl of 1 to 6 carbon atoms), AND NON-TOXIC, PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THE SALTS ARE USEFUL AS ANTIARRHYTHMICS.
申请公布号 FI60562(C) 申请公布日期 1982.02.10
申请号 FI19760002027 申请日期 1976.07.12
申请人 DR KARL THOMAE GMBH 发明人 KUTTER EBERHARD;AUSTEL VOLKHARD;EBERLEIN WOLFGANG;HEIDER JOACHIM;KADATZ RUDOLF;KOBINGER WALTER;LILLIE CHRISTIAN
分类号 A61K31/47;A61K31/472;A61P9/06;C07D217/24;C07D221/22;(IPC1-7):C07D217/24 主分类号 A61K31/47
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