发明名称 |
Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one. |
摘要 |
Improved topical pharmaceutical compositions containing a pharmaceutically-active agent and the penetration enhancing agent 1-dodecylazacycloheptan-2-one are disclosed. This agent is used at selected levels in combination with certain C3-C4 diols or a 1-substituted azacycloalkyl-2-one. This composition provides marked transepidermal and percutaneous delivery of the selected pharmaceutically-active agent. A method of treating certain pathologies and conditions responsive to the selected active, systemically or locally, is also disclosed. |
申请公布号 |
EP0129284(A2) |
申请公布日期 |
1984.12.27 |
申请号 |
EP19840200822 |
申请日期 |
1984.06.12 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
COOPER, EUGENE REX |
分类号 |
A61K9/06;A61K9/70;A61K31/52;A61K31/57;A61K47/08;A61K47/22 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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