发明名称 Cyclic amine modulators of chemokine receptor activity
摘要 The present invention is directed to cyclic amines of formula (I), (wherein R<1>, R<2>, R<3>, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.
申请公布号 AU8576098(A) 申请公布日期 1999.02.16
申请号 AU19980085760 申请日期 1998.07.21
申请人 MERCK & CO., INC. 发明人 CHARLES G CALDWELL;PAUL E. FINKE;MALCOLM MACCOSS;LAURA C. MEURER;SANDER G. MILLS;BRYAN OATES
分类号 C07D295/12;A61K31/445;A61K31/4453;A61K31/4468;A61K31/45;A61K31/451;A61K31/4525;A61K31/4535;A61K31/454;A61K31/4545;A61K31/498;A61K31/517;A61K31/535;A61K31/5375;A61K31/5377;A61K31/538;A61P9/10;A61P11/06;A61P19/02;A61P29/00;A61P31/18;A61P37/04;A61P37/08;A61P43/00;C07D211/14;C07D211/18;C07D211/22;C07D211/32;C07D211/34;C07D211/52;C07D211/58;C07D211/64;C07D211/76;C07D401/04;C07D401/06;C07D401/12;C07D403/04;C07D405/06;C07D405/12;C07D407/04;C07D409/06;C07D409/12;C07D413/04;C07D471/10 主分类号 C07D295/12
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