发明名称 |
Piperazin-2-one amides as inhibitors of factor xa |
摘要 |
Novel piperazin-2-one containing compounds of general formulae (I) or (II), including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivative having activity against mammalian factor Xa arc described. Compositions containing such compounds are also described. The compounds and the compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis. |
申请公布号 |
AU1128002(A) |
申请公布日期 |
2002.04.08 |
申请号 |
AU20020011280 |
申请日期 |
2001.10.01 |
申请人 |
COR THERAPEUTICS, INC. |
发明人 |
BING-YAN ZHU;TING SU;WENHAO LI;ERICK A. GOLDMAN;PENGLIE ZHANG;ZHAOZHONG JON JIA;ROBERT M. SCARBOROUGH JR. |
分类号 |
C07D241/06;A61K31/438;A61K31/495;A61K31/496;A61P7/02;A61P9/00;A61P9/10;C07D241/08;C07D401/10;C07D401/14;C07D403/10;C07D403/12;C07D403/14;C07D405/14;C07D409/12;C07D409/14;C07D491/10;C07D491/113 |
主分类号 |
C07D241/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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