发明名称 RNA-CODED ANTIBODY
摘要 The present application describes an antibody-coding, non-modified or modified RNA and the use thereof for expression of this antibody, for the preparation of a pharmaceutical composition, in particular a passive vaccine, for treatment of tumours and cancer diseases, cardiovascular diseases, infectious diseases, autoimmune diseases, virus diseases and monogenetic diseases, e.g. also in gene therapy. The present invention furthermore describes an in vitro transcription method, in vitro methods for expression of this antibody using the RNA according to the invention and an in vivo method.
申请公布号 US2016168254(A1) 申请公布日期 2016.06.16
申请号 US201615015657 申请日期 2016.02.04
申请人 CureVac AG 发明人 HOERR Ingmar;PROBST Jochen;PASCOLO Steve
分类号 C07K16/28;C07K16/30 主分类号 C07K16/28
代理机构 代理人
主权项 1. A method of treating a subject comprising administering an effective amount of a pharmaceutical composition comprising mRNA encoding CD20-binding antibody.
地址 Tubingen DE