发明名称 AN ETHER OF 1-(2-HYDROXYETHYL)-3-METHYL-PYRAZOLIN-5-ONE PROCESSES FOR ITS PREPARATION AND ITS USE AS AN ANTITHROMBOTIC AGENT
摘要 1454733 1 - (2 - Beta - naphthoxyethyl)- 3 - methylpyrazolin - 5 - one BAYER AG 6 May 1975 [6 June 1974 11 July 1974] 18970/75 Heading C2C The invention comprises the title compound and its salts. In examples, it is prepared by reacting (1) 2-beta-naphthoxyethylhydrazine with an alkyl or benzyl acetoacetate or tetrolate, or (2) a 2-beta-naphthoxyethyl halide with 3-methylpyrazolin-5-one or its sodium derivative. Therapeutic compositions having antithrombotic and thrombolytic activity comprise the above compound or its salts, and may be administered orally, parenterally or rectally.
申请公布号 HK26877(A) 申请公布日期 1977.06.10
申请号 HK19770000268 申请日期 1977.06.02
申请人 BAYER AG 发明人 HORSTMANN H;SEUTER F;MENG K;MOELLER E;WEHINGER E
分类号 A61K31/415;A61P7/02;C07D231/20;(IPC1-7):C07D231/20;A61K31/41 主分类号 A61K31/415
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