摘要 |
A preparation for percutaneous administration comprising a substrate and, formed on at least one surface thereof, a pressure-sensitive adhesive layer containing an acrylic copolymer, 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole or an acid-addition salt thereof (benzimidazole compound), and 2-mercaptobenzimidazole, which is excellent in the percutaneous absorbability of the benzimidazole compound and the persistency of drug effects, and is improved in the stability of the benzimidazole compound as the active ingredient in the preparation.
|
申请人 |
NITTO DENKO CORPORATION;KANEBO, LTD.;MURAOKA, TAKATERU;INOSAKA, KEIGO;AKEMI, HITOSHI;KAWAGUCHI, HIROKO;OTSUKA, SABURO;TAKAHASHI, YOSHITERU |
发明人 |
MURAOKA, TAKATERU;INOSAKA, KEIGO;AKEMI, HITOSHI;KAWAGUCHI, HIROKO;OTSUKA, SABURO;TAKAHASHI, YOSHITERU |