发明名称 |
Transdominant negative proto-oncogene |
摘要 |
The present invention provides a transrepressing protein of the Fos proto-oncogene family. The protein, FosB2, is characterized by having a leucine zipper domain and forming a heterodimer with a Jun related protein. This heterodimer is capable of binding to an AP-1 site and suppressing transcriptional transactivation of a promoter containing the AP-1 site.
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申请公布号 |
US6008323(A) |
申请公布日期 |
1999.12.28 |
申请号 |
US19950460242 |
申请日期 |
1995.06.02 |
申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
VERMA, INDER M.;WISDOM, RONALD M.;YEN, JONG-YOUNG J. |
分类号 |
C07K14/82;C12N15/12;(IPC1-7):C07K14/82 |
主分类号 |
C07K14/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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