发明名称 Novel antiestrogens, a method for the production thereof, and their pharmaceutical application
摘要 This invention relates to new antiestrogens of the general formula in which the substituents have the meanings that are explained in more detail in the description. The new compounds are a) pure antiestrogens or b) antiestrogens with partial estrogenic action (tissue-selective estrogens). Based on these properties, the new compounds are suitable for the production of pharmaceutical agents: in the case of a), for example, for the treatment of breast cancer; in the case of b), for example, for hormone replacement therapy.
申请公布号 AU4771699(A) 申请公布日期 1999.12.30
申请号 AU19990047716 申请日期 1999.06.09
申请人 SCHERING AKTIENGESELLSCHAFT 发明人 ULRICH KLAR;DR. ROLF BOHLMANN;KARSTEN PARCZYK;KARL-HEINRICH FRITZEMEIER;MONIKA LESSL;ROSEMARIE LICHTNER
分类号 C07D295/08;A61K9/127;A61K31/085;A61K31/10;A61K31/135;A61K31/336;A61K31/40;A61K31/4465;A61K31/45;A61P5/32;A61P35/00;C07C43/23;C07C217/14;C07C275/08;C07C317/18;C07C323/12;C07D303/16;C07D303/22;C07D303/26;C07D303/34 主分类号 C07D295/08
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