| 发明名称 |
Use of granulysin as an antimicrobial agent |
| 摘要 |
The T cell activation marker, granulysin, is demonstrated to be an effective antimicrobial agent. It is used in vitro and in vivo to reduce the population of viable cells in a microbial population. Of particular interest is the use of the active fragment of human granulysin, or modified forms thereof, to treat bacterial infections.
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| 申请公布号 |
US6485928(B2) |
申请公布日期 |
2002.11.26 |
| 申请号 |
US19980185245 |
申请日期 |
1998.11.03 |
| 申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
STENGER STEFFEN;MODLIN ROBERT L.;HANSON DENNIS ALAN;KRENSKY ALAN M.;JENNINGS SUSAN VALERIE |
| 分类号 |
A61K38/17;A61P31/00;(IPC1-7):A61K35/14;G01N33/574;G01N33/53;G01N33/569;G01N33/554 |
主分类号 |
A61K38/17 |
| 代理机构 |
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